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Revert20 mg+40 mg
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Medicine overview
Indications of Revert 20 mg+40 mg
ear buzzing (tinnitus)vascular headacheunsociability and irritabilityfatiguesleep rhythm disorders such as premature awakeninginvolutional depressionsloss of memory and lack of concentrationear buzzing (tinnitus)vascular headacheunsociability and irritabilityfatiguesleep rhythm disorders such as premature awakeninginvolutional depressionsloss of memory and lack of concentrationthromboangitis obliteransRaynaud's diseasediabetesacrocyanosis pernioetc.) such as intermittent claudicationtrophic disturbancespregangrenetrophic and varicose ulcersparaesthesianocturnal crampsvestibular irritabilityMeniere's syndrome such as vertigodizzinessgiddinesssyncopal attackstinnitusnystagmusnausea and vomiting. Prophylaxis of motion sickness.
Theropeutic Class
Anti vertigo drugs
Pharmacology
Cinnarizine provides faster relief of various symptoms of cerebral and peripheral circulation disorders and prevents attacks of vascular headache such as migraine.
Absorption
Cinnarizine normalizes cerebral circulation time and curves and improves cerebral irrigation in patients suffering from cerebral circulation disorders. Cinnarizine normalizes arterial pulsations in patients suffering from vasospastic disorders (Raynaud's disease).
Distribution
Cinnarizine significantly increases the rate of inflow of pulsations and the blood flow in the most affected limbs as well as the walking distance of patients suffering from intermittent claudication. Cinnarizine reduces the healing time of crural ulcers.
Metabolism
Dimenhydrinate acts as antihistamine with anti-cholinergic properties. The substance exhibits the anti-emetic & anti vertigo effects through influencing the chemoreceptor trigger zone.
Excretion
Cinnarizine reduces or eliminates symptoms of vestibular disturbances like, vertigo, tinnitus and autonomic manifestations (nausea, vomiting, pallor and cold extremities) and reduces or prevents future episodes.
Dosage & Administration of Revert 20 mg+40 mg
Usual adult dose
Dosage:1 tablet three times daily to be taken with liquid after meal or as advised by the physician
Children (under the age of 18)
Dosage:Not recommended
| Condition | Dosage | Notes |
|---|---|---|
| Usual adult dose | 1 tablet three times daily to be taken with liquid after meal or as advised by the physician | |
| Children (under the age of 18) | Not recommended |
Dosage of Revert 20 mg+40 mg
Adults
Dosage:1 tablet three times daily, to be taken after meals
Children andadolescents under the age of 18 years
Dosage:Not recommended Elderly: Dosage as for adults
| Condition | Dosage | Notes |
|---|---|---|
| Adults | 1 tablet three times daily, to be taken after meals | |
| Children andadolescents under the age of 18 years | Not recommended Elderly: Dosage as for adults |
Interaction of Revert 20 mg+40 mg
Concurrent use of alcohol, CNS depressants or tricyclic antidepressants may potentiate the sedative effects of either these drugs or of Cinnarizine and Dimenhydrinate. Therefore, it is advisable to avoid these drugs while taking Cinnarizine and Dimenhydrinate.
Contraindications
Cinnarizine and Dimenhydrinate should not be used by patients with severe hepatic impairment. Cinnarizine and Dimenhydrinate is contra-indicated in patients with known hypersensitivity to the active substances or to any of the excipients. Cinnarizine and Dimenhydrinate should not be used in patients with angle-closure glaucoma, convulsions, suspicion of raised intracranial pressure, and alcohol abuse or urine retention due to urethroprostatic disorders.
Side Effects of Revert 20 mg+40 mg
Drowsiness, dry mouth, headache, and stomach pain may occur. Rare side effects are impaired vision, allergic reactions, light sensitivity, and difficulty in urinating. Other possible reactions which may occur: weight gain, constipation, tightness of the chest, jaundice, worsening of angle-closure glaucoma, uncontrollable movements, unusual excitement and restlessness, severe skin reactions.
Pregnancy & Lactation
The safety of the combination of Cinnarizine & Dimenhydrinate in human pregnancy has not been established. The combination of Cinnarizine & Dimenhydrinate is excreted in human breast milk and should not be taken by women who are breast feeding.
Precautions & Warnings
Cinnarizine and Dimenhydrinate do not reduce blood pressure significantly; however, it should be used with caution in hypotensive patients. Cinnarizine and Dimenhydrinate should be taken after meals to minimize any gastric irritation. Caution should be exercised when administering Cinnarizine and Dimenhydrinate to patients with Parkinson’s disease.
Overdose Effects of Revert 20 mg+40 mg
Drowsiness, dizziness and ataxia with anticholinergic effects such as dry mouth, flushing of the face, dilated pupils, tachycardia, pyrexia, headache and urinary retention. General supportive measures should be used to treat respiratory insufficiency or circulatory failure. Gastric lavage with isotonic sodium chloride solution is recommended.
Storage Conditions
Store in a cool (below 30°C) and dry place. Keep away from light and out of reach of children.
Drug Classes
Anti vertigo drugs
Mode Of Action
This contains two active ingredients Cinnarizine and Dimenhydrinate. The two substances belong to different groups of medicines. Cinnarizine is part of a group called calcium antagonists. Dimenhydrinate belongs to a group called antihistamines. Both substances work by reducing symptoms of vertigo (a feeling of dizziness or spinning) and nausea (feeling sick). The combination product is more effective than the individual compounds.
Pregnancy
Dimenhydrinate and cinnarizine should not be used during pregnancy and lactation.
Frequently Asked Questions
What is Revert 20 mg+40 mg used for?
Cerebral circulatory disorders: Prophylaxis and maintenance therapy for symptoms of cerebral vascular spasms and arteriosclerosis such as: dizziness, ear buzzing (tinnitus), vascular headache, unsociability and irritability, fatigue, sleep rhythm disorders such as premature awakening, involutional depressions, loss of memory and lack of concentration, incontinence and other disorders due to aging.…
What is the dosage of Revert 20 mg+40 mg?
Adults: 1 tablet three times daily, to be taken after meals. Children andadolescents under the age of 18 years: Not recommended Elderly: Dosage as for adults.
What are the side effects of Revert 20 mg+40 mg?
Drowsiness, dry mouth, headache, and stomach pain may occur. Rare side effects are impaired vision, allergic reactions, light sensitivity, and difficulty in urinating. Other possible reactions which may occur: weight gain, constipation, tightness of the chest, jaundice, worsening of angle-closure glaucoma, uncontrollable movements, unusual excitement and restlessness, severe skin reactions.
Who should not take Revert 20 mg+40 mg?
Cinnarizine and Dimenhydrinate should not be used by patients with severe hepatic impairment. Cinnarizine and Dimenhydrinate is contra-indicated in patients with known hypersensitivity to the active substances or to any of the excipients. Cinnarizine and Dimenhydrinate should not be used in patients with angle-closure glaucoma, convulsions, suspicion of raised intracranial pressure, and alcohol ab…
What precautions should be taken with Revert 20 mg+40 mg?
Cinnarizine and Dimenhydrinate do not reduce blood pressure significantly; however, it should be used with caution in hypotensive patients. Cinnarizine and Dimenhydrinate should be taken after meals to minimize any gastric irritation. Caution should be exercised when administering Cinnarizine and Dimenhydrinate to patients with Parkinson’s disease.
Is Revert 20 mg+40 mg safe during pregnancy and breastfeeding?
The safety of the combination of Cinnarizine & Dimenhydrinate in human pregnancy has not been established. The combination of Cinnarizine & Dimenhydrinate is excreted in human breast milk and should not be taken by women who are breast feeding.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.