Sinakof50 mg

Sinakof 50 mg is used to relieve dry (non-productive) cough. Dry cough may be caused by a recent viral infection. Sinakof 50 mg is also used for pre & post-operative cough sedation in patients who will undergo surgical procedures and bronchoscopy. It can be used in the acute cough of any ... Read moreSinakof 50 mg is used to relieve dry (non-productive) cough. Dry cough may be caused by a recent viral infection. Sinakof 50 mg is also used for pre & post-operative cough sedation in patients who will undergo surgical procedures and bronchoscopy. It can be used in the acute cough of any etiology, whooping cough and cough due to acute lower respiratory tract infections (tracheitis, laryngitis, bronchitis) etc.

Cough suppressant

Sinakof 50 mg belongs to the anti-cough medicines of central action. It exerts expectorant, moderate bronchodilating and anti-inflammatory action. Sinakof 50 mg also increases the spirometery indexes and blood oxygenation. It is safe and non-sedating which is neither chemically nor pharmacologically related to opium alkaloids. The active metabolites of Sinakof 50 mg have also antitussive action.

Tablet: Adult: 2-3 tablets daily at 8 to 12 hours intervals, Adolescents over 12 years old: 1-2 tablets daily. Syrup: Children (3-6 years): 5 ml 3 times daily, Children (6-12 years): 10 ml 3 times daily, Adolescent: 15 ml 3 times daily, Adult: 15 ml 4 times daily. Pediatric Drops: Children (1-3 years): 0.75 ml 4 times daily, Children (2 months-1 year): 0.50 ml 4 times daily.

Use in adult: Sinakof 50 mg 50 mg tablet: 2-3 tablets daily. Sinakof 50 mg syrup: 15 ml 4 times daily. Use in children & adolescents:Sinakof 50 mg 50 mg tablet: Adolescent over 12 years old: 1-2 tablets daily. Sinakof 50 mg syrup: Children (3-6 yrs): 5 ml 3 times daily. Children (6-12 yrs): 10 ml 3 times daily. Adolescent: 15 ml 3 times daily. Sinakof 50 mg pediatric drops: Children ( 2 months- 1 yrs): 0.50 ml 4 times daily. Children (1-3 yrs): 0.75 ml 4 times daily.

Concomitant use with expectorants should be avoided.

Hypersensitivity to the active ingredient.

Tolerance of Sinakof 50 mg is good.Adverse reactions such as rash,nausea,diarrhoea and vertigo have been observed in a few rare cases,resolving after dose reduction or treatment withdrawal.

Sinakof 50 mg should not be used during the first trimester of pregnancy. During the remainder of pregnancy, it can be used if indicated by a physician but with caution. As a general rule, for safety reasons, in the absence of data on elimination of the active substance in breast milk, the benefits of Sinakof 50 mg administration during breast feeding should be carefully weighed against the risks.

Sinakof 50 mg suppresses the cough reflex and therefore the concomitant use with expectorants should be avoided, since it may lead to mucus retention in the airways, which increases the risk of bronchospasm and respiratory infections. If the cough persists for more than 7 days (more than 3 days in children younger than12 years of age) doctor must be consulted.

Accidental overdose with Sinakof 50 mg can cause the following symptoms: drowsiness, nausea, vomiting, diarrhoea, loss of balance and hypotension. Standard emergency procedures should be followed: activated charcoal, saline laxatives and standard cardio-respiratory resuscitation.

Keep away from light and moisture, store below 30°C. Keep all the medicines out of the reach of children.

Cough suppressant

Sinakof 50 mg acts directly on the brain's cough center to suppress cough. Sinakof 50 mg is safe and non-sedating which is neither chemically nor pharmacologically related to opium alkaloids. Sinakof 50 mg is rapidly and completely absorbed after oral administration. Maximum concentration is reached within 9 hours with the sustained-release tablet. This is extremely protein-bound and plasma elimination half-life is about 13 hours. The active metabolites of Sinakof 50 mg have also antitussive action.

Sinakof 50 mg should not be used during the first trimester of pregnancy. During the remainder of pregnancy, it can be used if indicated by a physician but with caution. As a general rule, for safety reasons, in the absence of data on elimination of the active substance in breast milk, the benefits of Sinakof 50 mg administration during breast feeding should be carefully weighed against the risks.