Histacin100 ml
Jayson Pharma Ltd.
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Sinamin100 ml
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Medicine overview
Indications of Sinamin 100 ml
Sinamin 100 ml is indicated in the following indications-
Urticaria
Sensitivity reactions
Angioneurotic edema
Vasomotor rhinitis
Cough
Common cold
Motion sickness and
Other allergic conditions.
Theropeutic Class
Sedating Anti-histamine
Pharmacology
Chlorpheniramine is an alkylamine antihistamine.
Absorption
Chlorpheniramine is not so prone to produce drowsiness, readily absorbed from the gastro-intestinal tract, metabolised in the liver and excreted usually mainly as metabolised in the urine.
Metabolism
Chlorpheniramine is not so prone to produce drowsiness, readily absorbed from the gastro-intestinal tract, metabolised in the liver and excreted usually mainly as metabolised in the urine.
Excretion
Chlorpheniramine is not so prone to produce drowsiness, readily absorbed from the gastro-intestinal tract, metabolised in the liver and excreted usually mainly as metabolised in the urine.
Dosage & Administration of Sinamin 100 ml
Adults
Dosage:4 mg 3-4 times daily
Children
Dosage:Up to 1( one) year: 1 mg twice daily 1-5 years: 1 mg 3-4 times daily 6-12 years: 2 mg 3-4 times daily or as directed by the physician
| Condition | Dosage | Notes |
|---|---|---|
| Adults | 4 mg 3-4 times daily | |
| Children | Up to 1( one) year: 1 mg twice daily 1-5 years: 1 mg 3-4 times daily 6-12 years: 2 mg 3-4 times daily or as directed by the physician |
Dosage of Sinamin 100 ml
Notes:Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily
Child- 6-12 years
Dosage:2 mg every 4-6 hours, maximum 12 mg daily
Notes:2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily. 1-2 years: 1 mg twice daily. Below 1 year the use of Sinamin 100 ml is not recommended
| Condition | Dosage | Notes |
|---|---|---|
| Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily | ||
| Child- 6-12 years | 2 mg every 4-6 hours, maximum 12 mg daily | 2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily. 1-2 years: 1 mg twice daily. Below 1 year the use of Sinamin 100 ml is not recommended |
Interaction of Sinamin 100 ml
Chlorphenamine maleate has been reported to be incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium, and meglumine adipiodone.
Contraindications
Chlorpheniramine is contraindicated in patients hypersensitive to this agent, in newborn or premature infants.
Side Effects of Sinamin 100 ml
Chlorpheniramine is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.
Pregnancy & Lactation
Pregnancy Category B. Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
Precautions & Warnings
Chlorpheniramine should be used with caution in patients with glaucoma and prostatic hypertrophy. During therapy with chlorpheniramine, caution should be taken in driving vehicles and operating machinery.
Overdose Effects of Sinamin 100 ml
CNS depression (including sedation, apnea, CV collapse), CNS stimulation (including insomnia, hallucination, tremors, convulsions), tinnitus, blurred vision, dizziness, ataxia, hypotension. Stimulation and atropine-like signs and symptoms (including dry mouth, fixed dilated pupils, flushing, hyperthermia, Gl symptoms) are more likely in children.
Storage Conditions
Store in a cool (Below 25°C temperature) and dry place protected from light. Keep out of the reach of children.
Drug Classes
Sedating Anti-histamine
Mode Of Action
Sinamin 100 ml is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Sinamin 100 ml exerts its effects by blocking H1-receptor competitively.
Pregnancy
This drug should not be used in lactating mother and in pregnancy especially during the first trimester of pregnancy.
Frequently Asked Questions
What is Sinamin 100 ml used for?
Chlorpheniramine Maleate is indicated in the following indications- Urticaria Sensitivity reactions Angioneurotic edema Vasomotor rhinitis Cough Common cold Motion sickness and Other allergic conditions.
What is the dosage of Sinamin 100 ml?
Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily. Child- 6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily. 2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily. 1-2 years: 1 mg twice daily. Below 1 year the use of Chlorpheniramine Maleate is not recommended.
What are the side effects of Sinamin 100 ml?
Chlorpheniramine is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.
Who should not take Sinamin 100 ml?
Chlorpheniramine is contraindicated in patients hypersensitive to this agent, in newborn or premature infants.
What precautions should be taken with Sinamin 100 ml?
Chlorpheniramine should be used with caution in patients with glaucoma and prostatic hypertrophy. During therapy with chlorpheniramine, caution should be taken in driving vehicles and operating machinery.
Is Sinamin 100 ml safe during pregnancy and breastfeeding?
Pregnancy Category B. Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.