Ursolic50 ml
Oral Suspension
Medicine overview
Indications of Ursolic 50 ml
Theropeutic Class
Pharmacology
Ursolic 50 ml is a naturally occurring bile acid used to treat different hepatobilliary disorders.
Ursolic 50 ml also promotes the formation of liquid cholesterol crystal complexes which enhance removal of the cholesterol from the gallbladder into the intestine to be expelled. Ursolic 50 ml improves cholestatic liver diseases by- Protecting cholangiocytes against cytotoxicity of hydrophobic bile acids Stimulating hepatobilliary secretion Protecting hepatocytes against bile acid-induced apoptosis Ursolic 50 ml is completely absorbed in the upper intestine.
Therefore, alters bile composition from supersaturated to unsaturated.
Ursolic 50 ml achieves this through a few mechanisms: it reduces cholesterol absorption, suppresses liver cholesterol synthesis and it does not inhibit bile acid synthesis. Ursolic 50 ml improves cholestatic liver diseases by- Protecting cholangiocytes against cytotoxicity of hydrophobic bile acids Stimulating hepatobilliary secretion Protecting hepatocytes against bile acid-induced apoptosis Ursolic 50 ml is completely absorbed in the upper intestine. After absorption Ursolic 50 ml enters the portal vein and undergoes extraction from portal blood by liver where it is conjugated with amino acid & that may be either glycine or taurine and then secreted into the hepatic bile ducts. The biologic half life of Ursolic 50 ml ranges from 3.5-5.8 days.
After absorption Ursolic 50 ml enters the portal vein and undergoes extraction from portal blood by liver where it is conjugated with amino acid & that may be either glycine or taurine and then secreted into the hepatic bile ducts. Small quantities of Ursolic 50 ml appear in the circulation and very small amounts are excreted into urine.
Dosage & Administration of Ursolic 50 ml
| Condition | Dosage | Notes |
|---|---|---|
| Dissolution of Gall stones | 8-12 mg/kg/day either as single night time dose or in divided dosesPBC: 10-15 mg/kg/day in 2-4 divided dosesAcute Viral Hepatitis: 600 mg/dayAlcoholic Fatty Liver: 300 mg/dayPSC: 25-30 mg/kg/dayNASH: 13-15 mg/kg/day |
Interaction of Ursolic 50 ml
Contraindications
Side Effects of Ursolic 50 ml
Pregnancy & Lactation
Precautions & Warnings
Storage Conditions
Frequently Asked Questions
What is Ursolic 50 ml used for?
Ursodeoxycholic Acid is indicated for the treatment of Cholestasis (Jaundice), Viral Hepatitis, Alcoholic Fatty Liver, Primary Billiary Cirrhosis (PBC), Primary Sclerosing Cholangitis (PSC), Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis (NASH).
What is the dosage of Ursolic 50 ml?
Dissolution of Gall stones: 8-12 mg/kg/day either as single night time dose or in divided dosesPBC: 10-15 mg/kg/day in 2-4 divided dosesAcute Viral Hepatitis: 600 mg/dayAlcoholic Fatty Liver: 300 mg/dayPSC: 25-30 mg/kg/dayNASH: 13-15 mg/kg/day
What are the side effects of Ursolic 50 ml?
Commonly reported side effects are nausea, vomiting, diarrhoea, gallstone opacilication, pruritus.
Who should not take Ursolic 50 ml?
Non-functioning gall-bladder calcified and pigmented gallstones, inflammatory bowel disease.
What precautions should be taken with Ursolic 50 ml?
It should be used cautiously in those with liver disease.
Is Ursolic 50 ml safe during pregnancy and breastfeeding?
Pregnancy category B. No evidence of harm has been reported in pregnancy. It has been effectively used for the treatment of cholestasis of pregnancy during the last trimester without any side effects. Problems have not been documented in humans regarding breast feeding.
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.