Diclofenac Sodium + Lidocaine Hydrochloride: Brands, Price & Uses in Bangladesh

Diclofenac Sodium + Lidocaine Hydrochloride injection is indicated for the short-term relief of acute pain and inflammation in a variety of musculoskeletal and post-traumatic conditions. Its established and commonly accepted uses include:

Established / Guideline-supported uses

• Acute exacerbations of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis
• Acute musculoskeletal disorders such as periarthritis (frozen shoulder), tendinitis, tenosynovitis, and bursitis
• Acute low back pain and post-traumatic pain and inflammation following sprains, strains, and fractures
• Post-operative pain and inflammation
• Acute gouty arthritis
• Renal and biliary colic (adjunct analgesic use)

Adjunct / symptomatic use

• Primary dysmenorrhea (short-term symptomatic relief of pain)

Diclofenac Sodium + Lidocaine Hydrochloride is intended for short-term intramuscular use only; the lidocaine component reduces pain at the injection site but does not extend the duration of analgesia. Long-term management of chronic inflammatory conditions should be continued with an oral or other appropriate formulation of diclofenac as advised by a physician.

Diclofenac Sodium + Lidocaine Hydrochloride is for deep intramuscular injection into the upper outer quadrant of the gluteal muscle only. It must never be given intravenously. Aspirate before injecting to avoid inadvertent intravascular administration.

Treatment with Diclofenac Sodium + Lidocaine Hydrochloride injection should generally not exceed 2 consecutive days; if further therapy is required, treatment should be continued with an oral, rectal, or other suitable formulation of diclofenac under medical supervision.

Most side effects of Diclofenac Sodium + Lidocaine Hydrochloride are mild and transient, but patients should be aware of the following:

Common

• Injection-site pain, induration, or discomfort
• Gastrointestinal discomfort, nausea, dyspepsia, or diarrhoea
• Headache and dizziness

Less common / serious

• Gastrointestinal ulceration or bleeding
• Elevated liver enzymes
• Fluid retention, oedema, or elevated blood pressure
• Rare injection-site reactions including local induration, abscess, or tissue necrosis
• Hypersensitivity reactions (skin rash, itching, rarely anaphylactoid reactions)
• Cardiovascular thrombotic events such as myocardial infarction or stroke (a recognised class effect of NSAIDs, more likely with prolonged use or in patients with cardiovascular risk factors)
• Signs of lidocaine systemic effect if absorbed in excess or inadvertently injected intravascularly — light-headedness, perioral numbness, tinnitus, blurred vision, tremor; rarely seizures or cardiac arrhythmia (see Precautions and Warnings)