Gabantin

Gabantin100 mg

Tablet

Gabapentin

Sun Pharmaceutical Ltd.

Product Code : 7660
MRP 6.02
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Medicine overview

Indications of Gabantin 100 mg

Gabantin 100 mg is indicated for- Neuropathic Pain. Adjunctive therapy in partial seizure and secondary generalized seizure.

Theropeutic Class

Adjunct anti-epileptic drugs

Pharmacology

Gabantin 100 mg is an anti-convulsant. It is a structural analog of gamma-amino-butyric-acid (GABA). All pharmacological actions following administration of Gabantin 100 mg are due to the activity of parent compound. Gabantin 100 mg binds with the alpha-2-delta subunit of voltage gated L-type Calcium channel, and inhibits branched chain amino acid transferase & probably inhibits neurotransmitter release of excitatory amino acid.

Dosage of Gabantin 100 mg

Neuropathic Pain: The treatment may be initiated as a single 300 mg dose on Day-1, than 300 mg twice on Day-2 and 300 mg thrice on Day-3. The dose can be subsequently be titrated up as needed for pain relief to a daily dose of 1800 mg (divided TID).Epilepsy: Patients over 12 years of age: the effective dose of Gabantin 100 mg is 900 to 1800 mg/day given in three divided doses. The starting dose is 300 mg three times a day. Paediatric patients age 3-12 year: the starting dose should range from 10-15 mg/kg/day in 3 divided doses, and the effective dose reached by upward titration over a period of approximately three days.

Administration of Gabantin 100 mg

Gabantin 100 mg can be taken orally with or without food.

Interaction of Gabantin 100 mg

Antacids may reduce the bioavailability of Gabantin 100 mg by up to 20 %. Cimetidine may alter its reanal excretion. Gabantin 100 mg does not interact with other anti-epileptic drug or with oral contraceptive preparations.

Contraindications

Gabantin 100 mg is contraindicated in patients who have known hypersensitivity to the drug.

Side Effects of Gabantin 100 mg

Fatigue, Dizziness, ataxia, weight gain, peripheral edema, dry mouth and somnolence may occur.

Pregnancy & Lactation

Pregnancy category C. it should be used during pregnancy only if potential benefits justifies the potential risk to the fetus. Gabantin 100 mg may be secreted through the breast milk. So it should be used during lactation only if potential benefits justifies the potential risk to the baby.

Precautions & Warnings

Patients should be instructed to take Gabantin 100 mg only as prescribed. While using Gabantin 100 mg patients should be instructed either not to drive a car or to operate other complex machinery until they have gained sufficient experiences about Gabantin 100 mg whether or not it affects their mental and/or motor performance adversely.

Storage Conditions

Store below 25°C temperature. Protect from light and moisture. Keep all the medicines out of the reach of the children.

Use In Special Populations

In case of renal impaired patients Gabantin 100 mg doses must be reduced.

Drug Classes

Adjunct anti-epileptic drugs

Mode Of Action

Gabantin 100 mg is an anti-convulsant. It is a structural analog of gamma-amino-butyric-acid (GABA). All pharmacological actions following administration of Gabantin 100 mg are due to the activity of parent compound. Gabantin 100 mg binds with the alpha-2-delta subunit of voltage gated L-type Calcium channel, and inhibits branched chain amino acid transferase & probably inhibits neurotransmitter release of excitatory amino acid.

Pregnancy

Pregnancy category C. it should be used during pregnancy only if potential benefits justifies the potential risk to the fetus. Gabantin 100 mg may be secreted through the breast milk. So it should be used during lactation only if potential benefits justifies the potential risk to the baby.

Pediatric Uses

In case of renal impaired patients Gabantin 100 mg doses must be reduced.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.