10% Off
Pitavas2 mg
Aristopharma Ltd.
৳90.00
Add to cart
Pivasta2 mg
Tablet
By
Best PriceTk /
1
Medicine overview
Indications of Pivasta 2 mg
Pitavastatin is indicated as an adjunctive therapy to diet to reduce elevated total cholesterol (TC)low-density lipoprotein cholesterol (LDL-C)apolipoprotein B (Apo B)triglycerides (TG) and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia.
Theropeutic Class
Other Anti-anginal & Anti-ischaemic drugs, Statins
Pharmacology
Pitavastatin lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and increases the number of hepatic LDL receptors on the cell surface for enhanced uptake and catabolism of LDL.
Dosage & Administration of Pivasta 2 mg
Notes:The dose range for Pitavastatin is 1 to 4 mg orally once daily at any time of the day with or without food. The recommended starting dose is 2 mg and the maximum dose is 4 mg. After initiation or upon titration of Pitavastatin, lipid levels should be analyzed after 4 weeks and the dosage adjusted accordingly
Dosage in Patients with Renal Impairment
Dosage:Patients with moderate renal impairment and end–stage renal disease receiving hemodialysis should receive a starting dose of Pitavastatin 1 mg once daily and a maximum dose of Pitavastatin 2 mg once daily
Notes:Pitavastatin should not be used in patients with severe renal impairment
| Condition | Dosage | Notes |
|---|---|---|
| The dose range for Pitavastatin is 1 to 4 mg orally once daily at any time of the day with or without food. The recommended starting dose is 2 mg and the maximum dose is 4 mg. After initiation or upon titration of Pitavastatin, lipid levels should be analyzed after 4 weeks and the dosage adjusted accordingly | ||
| Dosage in Patients with Renal Impairment | Patients with moderate renal impairment and end–stage renal disease receiving hemodialysis should receive a starting dose of Pitavastatin 1 mg once daily and a maximum dose of Pitavastatin 2 mg once daily | Pitavastatin should not be used in patients with severe renal impairment |
Dosage of Pivasta 2 mg
Notes:The dose range for Pitavastatin is 1 to 4 mg orally once daily at any time of the day with or without food. The recommended starting dose is 2 mg and the maximum dose is 4 mg. After initiation or upon titration of Pitavastatin, lipid levels should be analyzed after 4 weeks and the dosage adjusted accordingly
Dosage in Patients with Renal Impairment
Dosage:Patients with moderate renal impairment and end–stage renal disease receiving hemodialysis should receive a starting dose of Pitavastatin 1 mg once daily and a maximum dose of Pitavastatin 2 mg once daily
Notes:Pitavastatin should not be used in patients with severe renal impairment
| Condition | Dosage | Notes |
|---|---|---|
| The dose range for Pitavastatin is 1 to 4 mg orally once daily at any time of the day with or without food. The recommended starting dose is 2 mg and the maximum dose is 4 mg. After initiation or upon titration of Pitavastatin, lipid levels should be analyzed after 4 weeks and the dosage adjusted accordingly | ||
| Dosage in Patients with Renal Impairment | Patients with moderate renal impairment and end–stage renal disease receiving hemodialysis should receive a starting dose of Pitavastatin 1 mg once daily and a maximum dose of Pitavastatin 2 mg once daily | Pitavastatin should not be used in patients with severe renal impairment |
Interaction of Pivasta 2 mg
Cyclosporine: Co-administration of cyclosporine with Pitavastatin is contraindicated.Erythromycin: Erythromycin significantly increased Pitavastatin exposure. In patients taking erythromycin, a dose of Pitavastatin 1 mg once daily should not be exceeded.Rifampin: Rifampin significantly increased Pitavastatin exposure. In patients taking rifampin, a dose of Pitavastatin 2 mg once daily should not be exceeded.Fibrates: Pitavastatin should be administered with caution when used concomitantly with gemfibrozil or other fibrates.Warfarin: Pitavastatin had no significant pharmacokinetic interaction with warfarin.
Contraindications
Patients with a known hypersensitivity to any component of this product. Hypersensitivity reactions including rash, pruritus and urticaria have been reported with Pitavastatin. Patients with active liver disease which may include unexplained persistent elevations of hepatic transaminase levels.
Side Effects of Pivasta 2 mg
Rhabdomyolysis, myopathy and Liver enzyme abnormalities.
Pregnancy & Lactation
Pregnancy Category X. Pitavastatin is contraindicated in women who are or may become pregnant. It is not known whether Pitavastatin is excreted in human milk, however, it has been shown that a small amount of another drug in this class passes into human milk.
Precautions & Warnings
Pitavastatin should be prescribed with caution in patients with predisposing factors for myopathy. These factors include advanced age (>65 years), renal impairment, and inadequately treated hypothyroidism. Increase in serum transaminases have been reported with HMG-CoA reductase inhibitors, including Pitavastatin. In most cases, the elevations were transient and resolved or improved on continued therapy or after a brief interruption in therapy.
Overdose Effects of Pivasta 2 mg
There is no known specific treatment in the event of overdose of Pitavastatin. In the event of overdose, the patient should be treated symptomatically and supportive measures instituted as required. Hemodialysis is unlikely to be of benefit due to high protein binding ratio of Pitavastatin.
Storage Conditions
Store in a cool and dry place, protect from light & moisture . Keep out of the reach of children.
Drug Classes
Other Anti-anginal & Anti-ischaemic drugs, Statins
Mode Of Action
Pitavastatin lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and increases the number of hepatic LDL receptors on the cell surface for enhanced uptake and catabolism of LDL.
Pregnancy
Pregnancy Category X. Pitavastatin is contraindicated in women who are or may become pregnant. It is not known whether Pitavastatin is excreted in human milk, however, it has been shown that a small amount of another drug in this class passes into human milk.
Frequently Asked Questions
What is Pivasta 2 mg used for?
Pitavastatin is indicated as an adjunctive therapy to diet to reduce elevated total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG) and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia.
What is the dosage of Pivasta 2 mg?
The dose range for Pitavastatin is 1 to 4 mg orally once daily at any time of the day with or without food. The recommended starting dose is 2 mg and the maximum dose is 4 mg. After initiation or upon titration of Pitavastatin, lipid levels should be analyzed after 4 weeks and the dosage adjusted accordingly.Dosage in Patients with Renal Impairment: Patients with moderate renal impairment and end–…
What are the side effects of Pivasta 2 mg?
Rhabdomyolysis, myopathy and Liver enzyme abnormalities.
Who should not take Pivasta 2 mg?
Patients with a known hypersensitivity to any component of this product. Hypersensitivity reactions including rash, pruritus and urticaria have been reported with Pitavastatin. Patients with active liver disease which may include unexplained persistent elevations of hepatic transaminase levels.
What precautions should be taken with Pivasta 2 mg?
Pitavastatin should be prescribed with caution in patients with predisposing factors for myopathy. These factors include advanced age (>65 years), renal impairment, and inadequately treated hypothyroidism. Increase in serum transaminases have been reported with HMG-CoA reductase inhibitors, including Pitavastatin. In most cases, the elevations were transient and resolved or improved on continued t…
Is Pivasta 2 mg safe during pregnancy and breastfeeding?
Pregnancy Category X. Pitavastatin is contraindicated in women who are or may become pregnant. It is not known whether Pitavastatin is excreted in human milk, however, it has been shown that a small amount of another drug in this class passes into human milk.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.